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性腺机能减退

Overview

性腺机能减退 is a condition that causes decreased function of the gonads, which are the testes in males and the ovaries in females, 性激素分泌减少. You may be born with the condition or it can develop later in life from injury or infection. Some types of hypogonadism can be treated with hormone replacement therapy.

There are two forms of the condition – primary hypogonadism resulting from problems of the testis or ovary and central hypogonadism caused by problems with the pituitary or hypothalamic glands. Central hypogonadism leads to decreased levels of luteinizing hormone (LH) and follicle stimulating hormones (FSH), 由脑垂体释放的.

这种情况可能与遗传有关, 更年期, 自身免疫和病毒原因, or may develop after cancer treatments such as radiation and chemotherapy.

禁食, 减肥, stress and eating disorders such as anorexia nervosa and bulimia can also cause the condition.

我们治疗性腺功能减退的方法

UCSF is an international leader in 内分泌学 care. Our team provides comprehensive consultations, evaluations and treatments for a wide range of hormone disorders, 比如性腺功能减退.

男性和绝经前女性, we can usually treat hypogonadism successfully with hormone replacement therapy. We may also use hormonal treatments to restore fertility.

垂体肿瘤 cause some cases of hypogonadism, and treatment involves removing the tumor. UCSF surgeons pioneered a minimally invasive procedure to remove pituitary tumors, 叫做经蝶骨入路, which is safer than traditional surgery and leaves no scars. UCSF has more experience with this procedure than any other program in the nation and has a record of excellent outcomes.

奖 & 识别

迹象 & 症状

In children who have not reached puberty, hypogonadism causes no 症状. In adolescents, it can delay or prevent sexual development.

Adult women with the condition may stop menstruating or develop infertility, 失去性欲, 阴道干燥和潮热. Prolonged periods of hypogonadism can cause osteoporosis.

Men with the condition may experience 失去性欲, 勃起功能障碍, 潮热, 乳房生长和不孕.

诊断

诊断性腺功能减退, tests may be performed to check hormone levels – estogren in females and testosterone in males. 除了, levels of luteinizing hormone (LH) and follicle stimulating hormones (FSH) will be tested. LH and FSH are pituitary hormones that are stimulated by the gonads.

其他测试可能测量甲状腺激素, 精子数量和催乳素, a hormone 由脑垂体释放的 that stimulates breast development and milk production Tests also may be performed to test for anemia and possible genetic causes of 症状.

For women, your doctor may request a sonogram of your ovaries.

如怀疑有垂体疾病, a magnetic resonance imaging (MRI) scan or computed tomography (CT) scan may be performed to examine the the pituitary gland.

治疗

Hormone replacement therapy has proven to be effective treatment for hypogonadism in men and pre-更年期 women.

Estrogen may be administered in the form of a patch or pill. Testosterone can be given by a patch, a product soaked in by the gums, a gel or by injection.

For women who have not had their uterus removed, a combination of estrogen and progesterone is often recommended to decrease the chance of developing endometrial cancer. Low-dose testosterone may be added for women with hypogonadism who have a low sex drive.

Other hormones may be prescribed to restore fertility in men and women.

If the condition is caused by a pituitary tumor, treatment will include surgery to remove the tumor.

加州大学旧金山分校健康 medical specialists have reviewed this information. It is for educational purposes only and is not intended to replace the advice of your doctor or other health care provider. We encourage you to discuss any questions or concerns you may have with your provider.

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